Gauripur upazila on the north, Nandail upazila on the south, Kendua upazila on the east, Trishal on the west.

Ishwarganj thana, now an upazila, was established in 1936. The upazila consists of one municipality, 11 union parishads, 293 mouzas, 296 villages.

Ishwarganj Upazila is located in Mymensingh District. Upazilla(s)/Thana(s) in Mymensingh are Bhaluka Upazila, Dhobaura Upazila, Fulbaria Upazila, Gaffargaon Upazila, Gauripur Upazila, Haluaghat Upazila, Ishwarganj Upazila, Muktagachha Upazila, Mymensingh Sadar Upazila, Nandail Upazila, Phulpur Upazila, Trishal Upazila.